JOSE E. YANEZ, M.D.; GEORGE R. THOMPSON, M.D., F.A.C.P.; WILLIAM M. MIKKELSEN, M.D., F.A.C.P.; LEE E. BARTHOLOMEW, M.D., F.A.C.P.
Sir William Osler (1), in the sixth edition of his "Principles and Practice of Medicine," published in 1906, mentioned arthritis as a complication of rubella. However, the first series of cases in the English literature was described in 1918, when Geiger (2) reported 36 cases observed during an outbreak of rubella in North Little Rock, Ark. In four of these cases, hemolytic streptococci were cultured from the knee joint. One patient developed a permanent joint deformity, suggesting that some of the cases represented a complicating septic arthritis and not the benign arthritis we associate with rubella.
In 1940 an epidemic
JOSE E. YANEZ, GEORGE R. THOMPSON, WILLIAM M. MIKKELSEN, LEE E. BARTHOLOMEW. Rubella Arthritis. Ann Intern Med. 1966;64:772–777. doi: 10.7326/0003-4819-64-4-772
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Published: Ann Intern Med. 1966;64(4):772-777.
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