Gene H. Stollerman, M.D., F.A.C.P.
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If there has been a decline in the incidence and severity of rheumatic fever, one might expect this to be related to a change in the epidemiology of streptococcal disease. The two features of streptococcal infection that have been shown to be related most closely to the attack rate of rheumatic fever are the magnitude of the immune response and the duration of convalescent carriage of the infecting organism. Both of these features are, in turn, related to the virulence of the streptococcal strain causing the infection. The two most important factors related to virulence of group A streptococci are
Stollerman GH. The Changing Pattern of Rheumatic Fever.. Ann Intern Med. 1966;64:1151–1152. doi: 10.7326/0003-4819-64-5-1151_2
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Published: Ann Intern Med. 1966;64(5):1151-1152.
Infectious Disease, Rheumatology, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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