John C. Holmes, M.D. (Associate); Noble Fowler, M.D., F.A.C.P.; James A. Helmsworth, M.D.
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In local experience coronary arteriovenous fistula or aortic sinus of Valsalva aneurysm rupture into the right heart are the two common causes of continuous murmurs with systolic accentuation which are maximum over the lower sternum. This report describes three patients with coronary arteriovenous fistula subjected to successful surgical repair and five patients with anatomically verified aortic sinus aneurysm rupture, two of whom had successful repair.
Of the three patients with coronary arteriovenous fistula, two patients were 20-year-old women, the third was a 24-year-old man. Two had increased arterial pulse pressure and heart failure, and each had cardiac enlargement. The dilated
Holmes JC, Fowler N, Helmsworth JA. Coronary Arteriovenous Fistula and Aortic Sinus Aneurysm Rupture.. Ann Intern Med. 1966;64:1153. doi: 10.7326/0003-4819-64-5-1153_1
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Published: Ann Intern Med. 1966;64(5):1153.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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