Herbert Gershberg, M.D., F.A.C.P.; Dobroslav Matiasevic, M.D.; Zenaida C. Javier, M.D.
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Eighteen subjects with retarded growth were treated with human growth hormone (HGH) for up to 7 years. The group included 5 with idiopathic hypopituitarism, 1 with isolated growth hormone deficiency, 3 with achondroplasia and dyschondroplasia, 1 with vitamin D-resistant rickets, 1 with malabsorption resulting from massive resection of the small intestine, 1 with regional ileitis, 1 with gonadal dysgenesis, 2 with corticosteroid-induced dwarfism, 1 with Fanconi's anemia, 1 with glycogen-storage disease, and 1 with constitutional dwarfism.
Significant improvement in growth (at least twice the pretreatment rate) was most marked in the children with pituitary insufficiency and in the 2 children
Gershberg H, Matiasevic D, Javier ZC. Treatment and Metabolic Studies with Human Growth Hormone in Retarded Growth.. Ann Intern Med. ;64:1161. doi: 10.7326/0003-4819-64-5-1161_1
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Published: Ann Intern Med. 1966;64(5):1161.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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