Edward R. Burka, M.D.; Zebulon Weaver III, M.D.; Paul A. Marks, M.D.
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Deficiency of the erythrocyte enzyme glucose-6 phosphate dehydrogenase (G-6PD) is one of the most prevalent hereditary defects of clinical significance. Affected subjects are susceptible to hemolytic episodes after exposure to a large variety of agents or illnesses. One hundred and two patients with documented G-6PD deficiency have been retrospectively studied to determine the clinical characteristics of the associated hemolytic anemia. A total of 139 hemolytic episodes were found in 63 patients. These varied in severity from relatively benign, brief episodes to massive intravascular hemolysis. One hundred and nineteen of the episodes were acute (duration less than 2 months). Of these,
Burka ER, Weaver Z, Marks PA. Hemolytic Syndromes Associated with Glucose-6 Phosphate Dehydrogenase Deficiency.. Ann Intern Med. ;64:1164. doi: 10.7326/0003-4819-64-5-1164_1
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Published: Ann Intern Med. 1966;64(5):1164.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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