Lloyd C. Olson, M.D.; Malcolm S. Artenstein, M.D. (Associate); Paul D. Parkman, M.D.; Edward L. Buescher, M.D.
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Forty-seven patients with herpesvirus associated A with central nervous system (CNS) infections were divided into four groups: (1) 18 cases of encephalitis in which herpesvirus was isolated directly from CNS tissue; (2) 16 instances of encephalitis demonstrating a significant increase of complement-fixing or neutralizing antibody but without virus isolates; (3) 10 cases of aseptic meningitis associated with antibody rise; and (4) 3 patients with atypical illnesses with CNS symptoms who demonstrated antibody increase.
Analysis of group 1 revealed a clinical syndrome often beginning with fever and headache, CNS symptoms developing within 5 days. Nuchal rigidity, disturbances in consciousness and motor
Lloyd C. Olson, Malcolm S. Artenstein, Paul D. Parkman, Edward L. Buescher. Central Nervous System Infection with Herpesvirus Hominis.. Ann Intern Med. 1966;64:1168. doi: 10.7326/0003-4819-64-5-1168_2
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Published: Ann Intern Med. 1966;64(5):1168.
CNS Infections, Infectious Disease, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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