Sheldon J. Bleicher, M.D.; Martin G. Goldner, M.D., F.A.C.P.
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During the past 12 months, five patients with organic hypoglycemia were treated with diazoxide (200 to 400 mg/day), either alone or in combination with chlorothiazide (500 mg/day), utilizing the thiazide hyperglycemia as a therapeutic modality. One patient suffered from glycogenosis, the four others from functioning islet cell tumors. In three of these four patients, the diagnosis had been confirmed surgically: two patients had been operated upon previously, and their recurrent symptoms were due to metastases; one patient underwent surgical removal of the tumor after the treatment period. Plasma glucose and insulin levels (immunoassayable insulin), the excretion of catecholamines, 17-ketosteroids and
Sheldon J. Bleicher, Martin G. Goldner. Management of Organic Hypoglycemia with Thiazide Derivatives.. Ann Intern Med. 1966;64:1172. doi: 10.7326/0003-4819-64-5-1172_1
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Published: Ann Intern Med. 1966;64(5):1172.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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