Robert C. Muehrcke, M.D., F.A.C.P.; Seymour Rosen, M.D.; K. Gerhard Thiele, M.D.; Conrad L. Pirani, M.D.; Robert M. Kark, M.D., F.A.C.P.
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Drug-induced renal disease, like other iatrogenic disorders, bedevils the patient and humbles the physician when he finds that he has done harm at the time he thought he was doing good. Renal disease induced by drugs was studied by percutaneous biopsy in 40 patients. Clinical and laboratory findings were correlated with morphology, both by light and light and electron microscopy.
Thirty-one different drugs produced the following clinical entities: acute renal failure, acute hemorrhagic glomerulonephritis, the nephrotic syndrome, tubular disturbances, and chronic renal insufficiency.
Acute renal failure followed renal artery occlusion (triiodinated contrast medium). Zeek's sensitivity angiitis of the intralobular vessels
Muehrcke RC, Rosen S, Thiele KG, Pirani CL, Kark RM. Drug-induced Renal Disease.. Ann Intern Med. ;64:1181–1182. doi: 10.7326/0003-4819-64-5-1181_2
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Published: Ann Intern Med. 1966;64(5):1181-1182.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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