GERALD L. DENARDO, M.D.
Roentgenograms of the skeletal system frequently appear normal until late in the clinical course of bone disease (1-4). Bachman and Sproul (5) found roentgenographic changes in only 15 of 31 cases with spinal metastases at postmortem examination despite the antemortem use of tomography. Borak (6) demonstrated that 30 to 50% of the depth of a vertebra had to be lost before the change could be visualized roentgenographically. Abnormalities of the vertebrae, pelvis, sternum, ribs, and scapulae are particularly difficult to detect by conventional roentgenographic techniques. Because of the frequent inability of the routine roentgenogram to demonstrate lesions in the skeletal
DENARDO GL. The 85Sr Scintiscan in Bone Disease. Ann Intern Med. ;65:44–53. doi: 10.7326/0003-4819-65-1-44
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Published: Ann Intern Med. 1966;65(1):44-53.
Hematology/Oncology, Hospital Medicine.
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