CLIFFORD W. GURNEY, M.D.
Investigations of the mechanism of regulation of red cell production have received their impetus in recent years from the classical experiments of Reissman (1), which clearly established the existence of a humoral erythropoietic factor, and the studies of Jacobson, Plzak, Fried, and Goldwasser (2) and Jacobson, Gurney, and Goldwasser (3), which made available a series of simple, sensitive procedures for its bioassay. In the last 10 years, there has been rapid progress in understanding of the biochemical nature, mechanism of action, and role in both physiological erythropoiesis and abnormal states of red cell formation of erythropoietin, the hormonal regulator of
GURNEY CW. Erythropoietin and Erythropoiesis. Ann Intern Med. ;65:377–381. doi: 10.7326/0003-4819-65-2-377
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Published: Ann Intern Med. 1966;65(2):377-381.
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