GERALD P. RODNAN, M.D., F.A.C.P.; THOMAS G. BENEDEK, M.D.; WILLIAM C. PANETTA, PH.D.
The Fabric of the Joints in the Human Body is a Subject so much the more entertaining, as it must strike every one that considers it attentively with an Idea of fine mechanical composition.
—William Hunter, 1743 (1)
No part of the physiology of the bones abounds more in hypotheses and less in discoveries, than the history of the synovial system.
—Xavier Bichat, 1800 (2)
During the past few years there have been a renewal of interest in the study of synovia and increasing evidence of the importance of this fluid in various arthritic disorders. In this paper we propose
RODNAN GP, BENEDEK TG, PANETTA WC. The Early History of Synovia (Joint Fluid). Ann Intern Med. 1966;65:821–842. doi: 10.7326/0003-4819-65-4-821
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Published: Ann Intern Med. 1966;65(4):821-842.
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