GARY A. BECKER, M.D.; ENNIO C. ROSSI, M.D.
Hereditary persistence of fetal hemoglobin was first noted in 1955 by Edington and Lehmann (1). Subsequently, this condition was found in African and American Negroes (2-4), in a Portuguese-Indian family in England (5), and in Caucasians of Italian (6) and Greek ancestry (7). Conley and associates (8) found hereditary persistence of fetal hemoglobin in about 0.1% of the Negro population in Baltimore. Recently, this prevalence was confirmed by Thompson, Warrington, Odom, and Bell (9) in a survey of 12,000 Negroes in the southern United States. Thus, far more than 100 cases of hereditary persistence of fetal hemoglobin have been reported.
BECKER GA, ROSSI EC. The Interaction of Hereditary Persistence of Fetal Hemoglobin and Beta Thalassemia. Ann Intern Med. 1966;65:1071–1075. doi: 10.7326/0003-4819-65-5-1071
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Published: Ann Intern Med. 1966;65(5):1071-1075.
Hematology/Oncology, Red Cell Disorders.
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