ELIAS AMADOR, M.D.; E. JAMES POTCHEN, M.D.
The serum lactic dehydrogenase (LDH) activity is an accurate and sensitive tool for the detection and diagnosis of certain life-threatening cardiovascular diseases such as myocardial infarction and pulmonary embolism (1, 2). In the case of pulmonary embolism the high mortality has led to a critical evaluation of traditional methods employed for diagnosis with the findings that they have a limited diagnostic accuracy (3, 4). In contrast, studies of the serum LDH activity have shown that a persistently elevated LDH activity appears to be a sensitive and consistent index of pulmonary embolism (5-8); however, it is not specific per se.
AMADOR E, POTCHEN EJ. Serum Lactic Dehydrogenase Activity and Radioactive Lung Scanning in the Diagnosis of Pulmonary Embolism. Ann Intern Med. ;65:1247–1255. doi: 10.7326/0003-4819-65-6-1247
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Published: Ann Intern Med. 1966;65(6):1247-1255.
Emergency Medicine, Pulmonary Embolism, Pulmonary/Critical Care, Venous Thromboembolism.
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