The incidence of typhoid fever in the United States has declined steadily for many years. At the present time, less than 500 cases are reported annually, and a continuing downward trend can be expected. Cases are sporadic and are primarily related to contact with carriers rather than to common source exposure. Recognizing this epidemiologic pattern of typhoid fever, re-definition of the role and use of typhoid vaccine is indicated.
CURRENT STATUS OF TYPHOID VACCINE
Although typhoid vaccines have been employed for many decades, definitive evidence of their effectiveness has been accumulated only recently from well controlled field investigations.
Immunization Against Typhoid: Recommendation of the U. S. Public Health Service Advisory Committee on Immunization Practices1. Ann Intern Med. ;65:1300–1301. doi: 10.7326/0003-4819-65-6-1300
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Published: Ann Intern Med. 1966;65(6):1300-1301.
Infectious Disease, Prevention/Screening.
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