LUNG T. YAM, M.D.
In the pleural cavities of normal human subjects, there are small amounts of fluid that lubricate the linings. This fluid is minute in volume, difficult to obtain, and has not been studied extensively. When pleural effusions have accumulated and become clinically evident, they are easily available and are always of pathologic significance. Although cytologic examination of the effusions was recorded as early as in 1875 (1), reports dealing with the significance of cytologic patterns other than neoplastic cells are few and sporadic (2-8).
In the course of a clinical, cytologic, and histologic study of a group of patients with pleural
YAM LT. Diagnostic Significance of Lymphocytes in Pleural Effusions. Ann Intern Med. ;66:972–982. doi: 10.7326/0003-4819-66-5-972
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Published: Ann Intern Med. 1967;66(5):972-982.
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