E. J. H.
Calcium carbonate for the treatment of peptic ulcer has tended to give way, in recent years, to aluminum-magnesium antacids in part because they are less constipating and more palatable. However, calcium carbonate does continue in use as an antacid. Indeed, support for its continued use has come from a recent study by Fordtran and Collyns (1). They showed, using a test more closely resembling normal conditions than the usual assay, that calcium carbonate is superior to an aluminum-magnesium hydroxide preparation in postcibal reduction of gastric acidity and peptic activity. Calcium carbonate is not a drug without hazards, nevertheless, and severe
H. EJ. The Kidney and Oral Calcium Therapy. Ann Intern Med. ;66:1021–1022. doi: 10.7326/0003-4819-66-5-1021
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Published: Ann Intern Med. 1967;66(5):1021-1022.
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