J. William Fewell, M.D.; Felix M. Cortes, M.D.; Howard N. Baier, M.D.
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This study was devised to investigate the effects of reserpine on the normal and the diseased heart. The results of 5 of 15 patients are presented in this pilot study. The following parameters were measured at rest and during standardized exercise: mean arterial pressure, heart rate, ejection time, cardiac index, stroke index, and mean stroke ejection rate. The patient was given 1.0 mg of reserpine daily for 4 weeks, and the studies were repeated.
The normal patients demonstrated the following changes at rest while on reserpine: heart rate, -9%; ejection time, 0%; cardiac index, -63%; stroke index, -58%; and mean
Fewell JW, Cortes FM, Baier HN. Reserpine in the Diseased Heart.. Ann Intern Med. ;66:1036. doi: 10.7326/0003-4819-66-5-1036_1
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Published: Ann Intern Med. 1967;66(5):1036.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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