Perry G. Rigby, M.D.; Peyton T. Pratt, M.D. (Associate); Robert C. Rosenlof, M.D. (Associate); Henry M. Lemon, M.D., F.A.C.P.
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An investigation of the occurrence of leukemia and lymphoma in Nebraska has revealed 29 documented and 11 suspected multiple family instances of the coexistence of these disorders, mainly lymphoproliferative neoplasms. The consideration of these hemotologic malignancies together for the purpose of this study has been considered appropriate on the basis of pathological, clinical, therapeutic, prognostic, and presumed etiologic similarities, allowing for a variable expression of neoplastic potential implicit in a genetic or environmental factor concerned in causation (Rigby, Rosenlof, and Pratt, JAMA 197: 25, 1966).
The closeness of the genetic relationship in the majority of the involved family members is
Rigby PG, Pratt PT, Rosenlof RC, Lemon HM. Genetic Relationships in Familial Leukemia and Lymphoma.. Ann Intern Med. ;66:1043–1044. doi: 10.7326/0003-4819-66-5-1043_2
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Published: Ann Intern Med. 1967;66(5):1043-1044.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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