H. Thomas Norris, M.D. (Associate)
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The process by which the small bowel responds to the Vibrio cholerae or to its metabolic products with the typical outpouring of fluid remains poorly understood. It is commonly thought that inhibition of the sodium pump plays a significant role in the production of the diarrheal fluid. The present study is concerned with the response of the small bowel of the infant or adult rabbit to choleragen, a nonviable moiety of the Vibrio that produces a cholera-like syndrome in man and rabbit. After a lag period of 4 hr, large amounts of fluid pour into the lumen of the small
H. Thomas Norris. Changing Concepts in the Pathogenesis of Experimental Cholera.. Ann Intern Med. 1967;66:1047–1048. doi: 10.7326/0003-4819-66-5-1047_3
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Published: Ann Intern Med. 1967;66(5):1047-1048.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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