RALPH A. PINCUS, M.D., F.A.C.P.; SEYMOUR REICHLIN, M.D., PH.D.; L. H. HEMPELMANN, M.D.
Epidemiologic studies have clearly shown that radiation exposure plays a role in the induction of thyroid neoplasms in man (reviewed in references 1 and 2). In these studies, it has been observed that a large proportion of children and young adults with cancer of the thyroid give a history of prior X-ray treatment to the neck region and that the prevalence of thyroid cancers, adenomas, and nodules in irradiated populations is higher than in nonirradiated groups.
Although greatly in excess of that expected, the prevalence of thyroid neoplasms in irradiated groups reported in most prospective surveys is believed to be
PINCUS RA, REICHLIN S, HEMPELMANN LH. Thyroid Abnormalities After Radiation Exposure in Infancy. Ann Intern Med. ;66:1154–1164. doi: 10.7326/0003-4819-66-6-1154
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Published: Ann Intern Med. 1967;66(6):1154-1164.
Emergency Medicine, Endocrine and Metabolism, Thyroid Disorders.
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