AARNE KONTTINEN, M.D.
To the Editor: The article of Drs. Amador and Potchen (1) concerning the elevation of serum lactate dehydrogenase (LDH) activity in pulmonary embolism in the December issue of the ANNALS is worth some comments.
The authors of the article have observed an elevated serum LDH activity in 40 of 41 patients with pulmonary embolism. They refer also to some other investigations where a clear-cut augmentation of serum LDH activity has been reported in pulmonary damage. However, they omit a large bulk of studies in which the increase of serum LDH activity has been inconsistent.
On the other hand, the authors
KONTTINEN A. SERUM LACTATE DEHYDROGENASE AND PULMONARY EMBOLISM. Ann Intern Med. 1967;66:1291–1295. doi: 10.7326/0003-4819-66-6-1291
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Published: Ann Intern Med. 1967;66(6):1291-1295.
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