MICHAEL F. BALL, M.D.; JOHN J. CANARY, M.D., F.A.C.P.; LAURENCE H. KYLE, M.D., F.A.C.P.
Total starvation as a treatment of obesity was introduced by Bloom (1), popularized by Duncan and associates (2, 3), and elaborated upon by Drenick and colleagues (4, 5). An increasing number of reports concerning metabolic effects of this therapeutic approach are appearing (6-10), but only limited data exist concerning the effects of starvation on basic body constituents (11, 12). This study involves the use of densitometric, volume-distribution, and balance techniques to measure change in total body fat and lean body mass during both caloric restriction and total starvation.
The first study, involving five obese patients, was designed to compare loss
BALL MF, CANARY JJ, KYLE LH. Comparative Effects of Caloric Restriction and Total Starvation on Body Composition in Obesity. Ann Intern Med. ;67:60–67. doi: 10.7326/0003-4819-67-1-60
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Published: Ann Intern Med. 1967;67(1):60-67.
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