E. J. H.
Many cases of renal tubular acidosis and of the renal Fanconi syndrome appear, from their setting in familial patterns, to have some genetic basis. Nevertheless, both syndromes have occurred in cases that seem likely, by association at least, to be the consequence of a tubular injury acquired relatively late in adult life. This has been conspicuously true of the adult renal Fanconi syndrome (or syndrome of proximal-tubular dysfunction), many cases of which have been shown to be probable consequences of toxic injury to proximal tubular cells by such diverse agents as heavy metals and decomposition products of tetracycline. Other probable
E. J. H.. Renal Tubular Syndromes, Immunologic Disorders, and Cancer. Ann Intern Med. 1967;67:213–215. doi: 10.7326/0003-4819-67-1-213
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Published: Ann Intern Med. 1967;67(1):213-215.
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