ALTON I. SUTNICK, M.D., F.A.C.P.; Louis A. SOLOFF, M.D., F.A.C.P.
Local congestive atelectasis is a common occurrence with pulmonary infarction (1); its pathogenesis, however, is unclear. A prime role has been assigned to ischemic anoxia and subsequent reactive hyperemia from collateral bronchial arterial flow (2-5). The demonstration that pulmonary surfactant is secreted by alveolar epithelial cells (6) has raised the possibility that the altered metabolism of these cells may also be a factor. The purpose of this report is to examine the surface activity in extracts of human lungs involved with emboli and to attempt to relate these findings to the pathologic anatomic changes in the lung.
SUTNICK AI, SOLOFF LA. Pulmonary Arterial Occlusion and Surfactant Production in Humans. Ann Intern Med. 1967;67:549–555. doi: 10.7326/0003-4819-67-3-549
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Published: Ann Intern Med. 1967;67(3_Part_1):549-555.
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