JAMES BOYER, M.D.; GORDON N. GILL, M.D.; FRANKLIN H. EPSTEIN, M.D.
Hyperglycemia without ketosis may cause coma, convulsions, shock, and death (1-7). Severe disturbances in brain function are a consequence of the high concentration of glucose in the extracellular fluids resulting in intracellular dehydration.
Hypertonic glucose solutions are frequently used in peritoneal dialysis to remove edema. High levels of blood glucose have been observed during peritoneal dialysis (8-11), and large amounts of glucose are absorbed (9, 12). The tendency for serum sodium to be elevated after peritoneal dialysis with glucose solutions has also been commented on (10, 11, 13), but the explanation of this phenomenon is not widely appreciated.
BOYER J, GILL GN, EPSTEIN FH. Hyperglycemia and Hyperosmolality Complicating Peritoneal Dialysis. Ann Intern Med. ;67:568–572. doi: 10.7326/0003-4819-67-3-568
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Published: Ann Intern Med. 1967;67(3_Part_1):568-572.
Nephrology, Renal Replacement Therapy.
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