HERBERT A. SALTZMAN, M.D.
The physician administering oxygen to his patient usually hopes to accelerate the flow of this essential respiratory gas to hypoxic tissues. A rational alternative goal is to raise the concentration of oxygen within the body well above normal. Recently, the practical range of dosage for oxygen has increased greatly, reflecting the current availability of hyperbaric chambers (1). As a result, the modern therapist may overcome previously insuperable barriers to adequate oxygen delivery down a defective transport ladder. Unfortunately, he must also anticipate the more frequent occurrence of toxicity when treatment is intense and prolonged. Guidelines for effective, safe therapy are
SALTZMAN HA. Rational Normobaric and Hyperbaric Oxygen Therapy. Ann Intern Med. ;67:843–852. doi: 10.7326/0003-4819-67-4-843
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Published: Ann Intern Med. 1967;67(4):843-852.
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