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The description of the "LE cell" phenomenon and the rediscovery of rheumatoid factor in 1948 marked the beginning of an intensive effort to establish autoimmunity as the cause of a number of human diseases of unknown origin. Twenty years later no one now doubts that autoimmunity truly can develop in the course of a number of diseases, but autoimmune hemolytic anemia remains the only one in which we are reasonably sure autoantibodies play a pathogenetic role.
Drs. Anderson, Buchanan, and Goudie have made a number of significant contributions to the immunopathology of thyroid diseases during this period. They have written
Autoimmunity. Clinical and Experimental.. Ann Intern Med. 1967;67:1355–1356. doi: 10.7326/0003-4819-67-6-1355
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Published: Ann Intern Med. 1967;67(6):1355-1356.
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