JOHN LINDENBAUM, M.D.; R. LESLIE HARGROVE, M.D.
Ten episodes of thrombocytopenia in five chronic alcoholics with delirium tremens are described. Platelet counts rapidly returned to normal after withdrawal of alcohol with a subsequent thrombocytosis. None of the patients had cirrhosis, splenomegaly, or evidence of folic acid deficiency. Thrombocytopenia recurred in three patients 4 to 8 weeks after discharge from hospital and resumption of ethanol intake. It is postulated that the thrombocytopenia was a direct effect of alcohol intoxication by a mechanism as yet unknown.
LINDENBAUM J, HARGROVE RL. Thrombocytopenia in Alcoholics. Ann Intern Med. ;68:526–532. doi: 10.7326/0003-4819-68-3-526
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Published: Ann Intern Med. 1968;68(3):526-532.
Hematology/Oncology, Platelet Disorders, Tobacco, Alcohol, and Other Substance Abuse.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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