PRISCILLA KINCAID-SMITH, M.B., F.R.A.C.P., D.C.P.
Although 15 years have passed since this topic was first introduced (1), the controversy about the effect of analgesics on the kidney continues. Opposite views were expressed at a meeting devoted to this subject 10 years ago (2), and in spite of active research since then, many of the major questions about the nephrotoxic effects of analgesics remain unsolved.
The clinical syndrome is well-defined, and clinicians from many parts of the world would agree that the clearcut syndrome documented in the paper by Gault, Rudwal, Engles, and Dossetor (3) beginning on p. 906 of this issue can be recognized without
KINCAID-SMITH P. Analgesic Nephropathy. Ann Intern Med. ;68:949–952. doi: 10.7326/0003-4819-68-4-949
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Published: Ann Intern Med. 1968;68(4):949-952.
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