Billy J. Matter, M.D. (Associate); M. Earl Ginn, M.D.; James H. Shinaberger, M.D.; Joel B. Mann, M.D.
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Dialysis utilizing aqueous solutions is an established procedure in the treatment of poisoning due to water-soluble intoxicants. However, many frequently prescribed drugs with high lipid to water partition coefficients are not effectively removed by aqueous dialysate. To augment transfer of these compounds we developed a lipid dialysate system. Soybean oil was found to be effective and nontoxic. It is inexpensive and readily available. Due to the high solubility of these compounds in oil, only 1 to 5 gal need be used. Kiil, Klung, and twin-coil dialyzers have been successfully utilized. This technique has been effectively used in the clinical treatment
Matter BJ, Ginn ME, Shinaberger JH, Mann JB. Clinical Experience with Lipid Dialysate.. Ann Intern Med. 1968;68:1143. doi: 10.7326/0003-4819-68-5-1143_1
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Published: Ann Intern Med. 1968;68(5):1143.
Cardiology, Coronary Risk Factors, Dyslipidemia, Nephrology, Renal Replacement Therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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