CRAIG K. WALLACE, M.D.; EUGENE J. GANGAROSA, M.D.
A cholera pandemic, caused by Vibrio cholerae biotype El Tor, has spread from its endemic focus in Indonesia since 1960. Southeast and South Asia have been affected, and even now the Middle East is threatened. There is great concern about further extension by means of rapid ground and air travel from multiple-infected foci and a totally unpredictable pattern of geographic spread. Cholera terrorizes a population. It strikes swiftly. Mortality may exceed 60%, especially where medical facilities are inundated and practitioners are unfamiliar with treatment.
Therapy has been simple and dramatically successful since Watten and coworkers (1) introduced the concept that
WALLACE CK, GANGAROSA EJ. Antibiotic Drugs in Cholera. Ann Intern Med. ;69:166–167. doi: 10.7326/0003-4819-69-1-166
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Published: Ann Intern Med. 1968;69(1):166-167.
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