LLOYD J. OLD, M.D.; EDWARD A. BOYSE, M.D.
After a period of almost total eclipse, tumor immunology is again a thriving field of interest. The final recognition of tumor antigens, so long in coming, has profoundly influenced contemporary thought about cancer.
To begin with, these antigens represent qualitative distinctions between cancer cells and normal cells, contrary to earlier views that no such differences exist. Secondly, detection of these antigens by a variety of techniques adapted for the purpose provides approaches to determining the cause of various cancers; this is particularly obvious in the case of antigens specified by oncogenic viruses, although there are other tumor antigens that, as
OLD LJ, BOYSE EA. Prospects for Immunotherapy of Human Cancer. Ann Intern Med. ;69:393–397. doi: 10.7326/0003-4819-69-2-393
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Published: Ann Intern Med. 1968;69(2):393-397.
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