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As a primer for physicians embarking on a clinical study, this book seeks to fulfill a very important function. Each step involved in planning is carefully detailed, and stress is correctly placed on the importance of clearly defining questions to be solved by the study, the size of sample necessary, methods to avoid bias in selection of patients and in recording results, and the theory and value of pilot studies. Since the book is directed primarily to clinicians, mathematical content is kept to a bare minimum, although the importance of consultation with a statistician at every stage of planning is
Planning Clinical Experiments.. Ann Intern Med. 1968;69:644–645. doi: 10.7326/0003-4819-69-3-644_2
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Published: Ann Intern Med. 1968;69(3):644-645.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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