FRANCIS A. BREEN JR., M.D.; JAMES L. TULLIS, M.D.
The ability of ethanol to gel soluble fibrin (fibrin monomer) in an in vitro test system and its further applicability in clinical situations are reported. Five patients with clinically documented disseminated intravascular coagulation had positive ethanol gelation tests. Thirty-six others, including four with hypofibrinogenemia from primary fibrinolysis, were negative. The ethanol test described is a simple, rapid screening procedure to distinguish between hypofibrinogenemia due to disseminated intravascular coagulation and hypofibrinogenemia due to primary fibrinolysis.
BREEN FA, TULLIS JL. Ethanol Gelation: A Rapid Screening Test for Intravascular Coagulation. Ann Intern Med. ;69:1197–1206. doi: 10.7326/0003-4819-69-6-1197
Download citation file:
Published: Ann Intern Med. 1968;69(6):1197-1206.
Results provided by:
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use