RICHARD L. DEGOWIN, M.D.; LEIF B. SORENSEN, M.D.; DONALD B. CHARLESTON, M.S.; ALEXANDER GOTTSCHALK, M.D.; JAMES H. GREENWALD, M.D.
This paper presents studies of a menopausal woman with idiopathic pulmonary hemosiderosis who had only slight hemoptysis, no measurable blood loss, but a major intrapulmonary hemorrhage.
Labeled hemoglobin-iron sequestered in the lung could not be readily mobilized by the body or with an iron-chelating agent in the presence of an iron-responsive hypochromic anemia.
In this case, linear profile scanning proved helpful in the diagnosis of pulmonary hemorrhage.
Finally, idiopathic pulmonary hemosiderosis should be considered as a cause of unexplained cough, ephemeral pulmonary infiltrates, and iron-responsive hypochromic anemia in any age patient. Diagnosis may be made by looking for hemosiderin-laden macrophages in the sputum or gastric aspirates, and by performing radioisotope studies and a lung biopsy.
DEGOWIN RL, SORENSEN LB, CHARLESTON DB, GOTTSCHALK A, GREENWALD JH. Retention of Radioiron in the Lungs of a Woman with Idiopathic Pulmonary Hemosiderosis. Ann Intern Med. ;69:1213–1220. doi: 10.7326/0003-4819-69-6-1213
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Published: Ann Intern Med. 1968;69(6):1213-1220.
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