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There have been a number of publications on the ultrastructure of the thyroid in animals and man since 1953. Notable among these are papers by Ekholm, Heimann, Wissig, and Wollman, whose work indicates the basic similarity of the thyroid with the subcellular anatomy of other secretory cells and the marked changes in the structure associated with thyroid-stimulating hormone (TSH) stimulation. In the presence of TSH stimulation the cell develops on its apical surface elongated microvilli that are involved in endocytosis of colloid. Wollman has shown the fusion of lysosomes with colloid phagocytic droplets and indicated their involvement in the process
Ultrastructure of the Thyroid Gland.. Ann Intern Med. 1969;70:244–245. doi: 10.7326/0003-4819-70-1-244_2
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Published: Ann Intern Med. 1969;70(1):244-245.
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