MONROE COLE, M.D., F.A.C.P.
Are oral contraceptive hormones potentially harmful? The question, important enough itself, is related to the greater problem of proving the safety of any widely used drug or treatment. The problem of oral contraceptives is unique in that a large portion of the healthy population is "treated" despite availability of adequate, albeit inconvenient, methods to achieve the same end. The argument that pregnancy itself bears risks to health is a sophism because the use of contraceptive hormones is not the only way to prevent pregnancy.
Numerous medical problems have been reported in patients using oral contraceptive hormones, the most serious of
COLE M. Oral Contraceptives and Proof of Drug Safety. Ann Intern Med. ;70:868. doi: 10.7326/0003-4819-70-4-868
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Published: Ann Intern Med. 1969;70(4):868.
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