BRENT M. PARKER, M.D.
Eighteen patients with idiopathic hypertrophic muscular subarotic stenosis (IHSS) have been followed for an average period of 4 years. During follow-up there has been improvement or no change in 17 patients. Two patients have improved with propranolol. No patient has had surgery, and none has died. This result is contrasted with a 19% mortality in reported surgical cases. Some of the surgical survivors have potentially serious complications, and follow-up data are sparse.
The results of this study suggest that IHSS is a disease of slow progression in most patients and that surgery should be reserved for those patients who have disabling symptoms that do not respond to medical therapy.
PARKER BM. The Course in Idiopathic Hypertrophic Muscular Subaortic Stenosis. Ann Intern Med. ;70:903–911. doi: 10.7326/0003-4819-70-5-903
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Published: Ann Intern Med. 1969;70(5):903-911.
Cardiology, Valvular Heart Disease.
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