J. Richard Crout, M.D., F.A.C.P.; Burnell R. Brown Jr., M.D.; Federico A. Dostal, M.D.
This content is PDF only. Please click on the PDF icon to access.
Since January 1964 the diagnosis of pheochromocytoma has been established in 20 patients on the basis of urinary catecholamine studies performed in this laboratory. Six were members of 2 separate families harboring pheochromocytoma, while the remaining 14 developed tumors in the absence of genetic predisposition. Urinary free norepinephrine was increased in 90% of patients, free epinephrine in 55%, normetanephrine and metanephrine in 100%, and vanilmandelic acid in 95%. Mean excretion values for the group, although markedly elevated, were only about one third of those reported in a similar series in 1964 (CROUT, J. R., SJOERDSMA, A.: J. Clin. Invest. 43:
J. Richard Crout, Burnell R. Brown, Federico A. Dostal. Current Experience with Pheochromocytoma.. Ann Intern Med. 1969;70:1061–1062. doi: 10.7326/0003-4819-70-5-1061_3
Download citation file:
Published: Ann Intern Med. 1969;70(5):1061-1062.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use