J. Richard Crout, M.D., F.A.C.P.; Burnell R. Brown Jr., M.D.; Federico A. Dostal, M.D.
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Since January 1964 the diagnosis of pheochromocytoma has been established in 20 patients on the basis of urinary catecholamine studies performed in this laboratory. Six were members of 2 separate families harboring pheochromocytoma, while the remaining 14 developed tumors in the absence of genetic predisposition. Urinary free norepinephrine was increased in 90% of patients, free epinephrine in 55%, normetanephrine and metanephrine in 100%, and vanilmandelic acid in 95%. Mean excretion values for the group, although markedly elevated, were only about one third of those reported in a similar series in 1964 (CROUT, J. R., SJOERDSMA, A.: J. Clin. Invest. 43:
Crout JR, Brown BR, Dostal FA. Current Experience with Pheochromocytoma.. Ann Intern Med. ;70:1061–1062. doi: 10.7326/0003-4819-70-5-1061_3
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Published: Ann Intern Med. 1969;70(5):1061-1062.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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