Lillian Haddock, M.D., F.A.C.P.; Luis A. Vega, M.D.; Ovidio Rodríguez, M.D.; Francisco Aguiló, M.D.
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Sheehan's syndrome is the most common cause of hypopituitarism in the indigent medical population of our University Hospital. The endocrine function was thoroughly studied in a group of patients diagnosed after 1960 and in some of the earlier cases.
Human growth hormone (HGH) was measured by immunoassay after insulin hypoglycemia, or arginine infusion, or both. Adrenocorticotrophic hormone (ACTH) reserve was measured indirectly by the response to metyrapone; thyroid reserve by the measurement of the 24-hr radioactive iodine uptake; the protein-bound iodine (PBI) before and after thyroid-stimulating hormone (TSH); and the adrenal reserve by the measurement of the daily excretion of
Lillian Haddock, Luis A. Vega, Ovidio Rodríguez, Francisco Aguiló. The Adrenocortical, Thyroidal, and Human Growth Hormone Reserve in Sheehan's Syndrome.. Ann Intern Med. 1969;70:1062. doi: 10.7326/0003-4819-70-5-1062_2
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Published: Ann Intern Med. 1969;70(5):1062.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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