J. E. Berk, M.D., F.A.C.P.; H. Kizu, M.D.; E. Geller, Ph.D.; L. Fridhandler, Ph.D.
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Macroamylasemia, a newly recognized cause of persistent elevation of serum amylase activity, appears to be commoner than might have been suspected. Clinical observatons and special biochemical determinations made in 12 cases that have been studied to date are reported. Only 3 of the 12 patients were men, and 10 of the 12 were white. Although no consistent symptom configuration was apparent, abdominal pain of variable severity was a complaint in eight cases. In six patients in whom an abdominal operation was performed, the pancreas was considered normal in five and showed a minor change of questionable signficance in the sixth.
Berk JE, Kizu H, Geller E, Fridhandler L. Macroamylasemia.. Ann Intern Med. 1969;70:1065–1066. doi: 10.7326/0003-4819-70-5-1065_3
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Published: Ann Intern Med. 1969;70(5):1065-1066.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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