M. J. Goldstein, M.D., F.A.C.P.; H. Schachter, M.D.; H. Rappaport, M.D., F.A.C.P.; J. J. Fennessy, M.D.; J. B. Kirsner, M.D., F.A.C.P.
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One hundred patients with inflammatory disease of the colon treated by total colectomy during 1936-67 were subjected to independent clinical, pathologic, and radiologic restudy. Twenty-one of the 100 patients were diagnosed clinically as having Crohn's disease ("granulomatous" colitis), with X-ray agreement in 18 cases. Only 6 of the 21 patients presented cumulative histologic features of granulomatous colitis, although even in these cases co-existent histologic features of ulcerative colitis were noted. Granulomas were found in 11 of the 21 patients, fissures or clefts in 3, and lymphangiectasis in none. Seventy-nine of the 100 patients were diagnosed clinically as having ulcerative colitis,
Goldstein MJ, Schachter H, Rappaport H, Fennessy JJ, Kirsner JB. Ulcerative and "Granulomatous" Colitis—Validity of Differential Criteria: A Study of 100 Patients Treated by Total Colectomy.. Ann Intern Med. ;70:1067–1068. doi: 10.7326/0003-4819-70-5-1067_3
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Published: Ann Intern Med. 1969;70(5):1067-1068.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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