Ramon R. Joseph, M.D., F.A.C.P.; Fred W. Whitehouse, M.D., F.A.C.P.
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Elevation of serum amylase in excess of 1,000 Somogyi units is not commonly associated with hepatic disorders. We have recently encountered five patients in whom the diagnosis of pancreatitis was initially made on the basis of marked elevation of the serum amylase but who were found to have fulminant hepatic disease at postmortem examination. Levels of serum amylase ranged from 1,060 to 1,300 Somogyi units. At autopsy one patient had miliary tuberculosis with extensive liver involvement and four had massive hepatic necrosis, thought to be due to viral hepatitis in three and to toxic hepatitis in one. None had significant
Joseph RR, Whitehouse FW. Hyperamylasemia as a Manifestation of Fatal Hepatic Disease.. Ann Intern Med. ;70:1068. doi: 10.7326/0003-4819-70-5-1068_2
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Published: Ann Intern Med. 1969;70(5):1068.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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