Joseph W. Linhart, M.D.; Frank J. Hildner, M.D.; S. Serge Barold, M.D.; Philip Samet, M.D.
This content is PDF only. Please click on the PDF icon to access.
Although recent investigations have elucidated most of the mechanisms of action of nitroglycerine, its effect upon left ventricular myocardial function is still not clear. Therefore, left ventricular function was determined during left heart catheterization before and after 0.4 to 0.6 mg nitroglycerin, sublingually, in 23 patients (18 men and 5 women) ranging in age from 41 to 68 years (mean, 54). Left ventricular function curves, relating stroke work to end-diastolic pressure, were constructed using a graded infusion of angiotensin to augment afterload. Sixteen of the 23 patients were shown to have significant coronary artery disease by cineangiography.
Nitroglycerin produced a
Linhart JW, Hildner FJ, Barold SS, Samet P. The Effect of Sublingual Nitroglycerin Upon Left Ventricular Myocardial Function.. Ann Intern Med. 1969;70:1079. doi: 10.7326/0003-4819-70-5-1079_1
Download citation file:
Published: Ann Intern Med. 1969;70(5):1079.
Results provided by:
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use