Hiltrud S. Mueller, M.D.; John J. Gregory, M.D., F.A.C.P.; Stephen M. Ayres, M.D., F.A.C.P.; Stanley Giannelli Jr., M.D.; William J. Grace, M.D., F.A.C.P.
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Metabolic differences between coronary and noncoronary cardiogenic shock may explain reported differences in response to sympathiocomimetic amines. Cardiac index (CI), mean aortic pressure (MAP), coronary blood flow (CBF), myocardial oxygen consumption (MVO2), oxygen, lactate, and pyruvate extraction ratios (ExO2, ExT, and Exn), and arterial lactate pyruvate ratios (L/P) were measured as follows: in five patients in noncoronary shock after mitral and aortic valve replacement; in eight patients in coronary shock after acute myocardial infarction; and in six patients in mixed shock after hemorrhage and sepsis.
The hemodynamics did not vary significantly between the three groups, except for coronary blood flow.
Mueller HS, Gregory JJ, Ayres SM, Giannelli S, Grace WJ. Hemodynamics, Myocardial Metabolism, and Therapeutical Response in Cardiogenic Noncoronary (NCS), Coronary (CS), and Mixed Shock (MS).. Ann Intern Med. ;70:1079. doi: 10.7326/0003-4819-70-5-1079_2
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Published: Ann Intern Med. 1969;70(5):1079.
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