Myron H. Weinberger, M.D.; R. Dennis Collins, M.D.; John A. Luetscher, M.D.
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Studies were performed on 80 hypertensive subjects. Thirteen of these patients, who were receiving oral contraceptive therapy when referred for evaluation, were studied during and after withdrawal of oral contraceptive therapy. Measurements of angiotensinogen concentration, plasma renin activity, and aldosterone excretion were made during conditions of standardized sodium intake and posture. The oral contraceptive therapy group demonstrated at least a 250% increase in angiotensinogen concentration in all cases studied, with a return to normal values after cessation.. Fifty percent of these patients demonstrated increases in plasma renin activity and aldosterone secretion during ingestion, with a return to normal values after
Weinberger MH, Collins RD, Luetscher JA. Contraceptive-Induced Hypertension: A Potentially Curable Form of Hypertension.. Ann Intern Med. ;70:1081–1082. doi: 10.7326/0003-4819-70-5-1081_3
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Published: Ann Intern Med. 1969;70(5):1081-1082.
Cardiology, Coronary Risk Factors, Hypertension, Infectious Disease, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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