Lewis H. Dennis, M.D.; M. Bernadette Garvey, F.R.C.P. (C); Jesse Hano, M.D.; Marcel E. Conrad, M.D., F.A.C.P.
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Recent work showed that heat stroke is a hypercoagulable state associated with classic findings of disseminated intravascular coagulation, including depression of labile clotting factors V and VIII, increased fibrinolytic activity, and the appearance of fibrinogen degradation products. To investigate this phenomenon coagulation studies were performed on heat-acclimatized and -unacclimatized individuals undergoing the standard exercise and combat proficiency test of the U. S. Army at Fort Sam Houston, Tex. Ambient temperatures during the period of investigation averaged 100 F. Studies were conducted immediately before and after exercise. These studies were first performed within 3 days after the subject arrived in a
Dennis LH, Garvey MB, Hano J, Conrad ME. Heat Stress: Effects Upon Coagulation.. Ann Intern Med. ;70:1082–1083. doi: 10.7326/0003-4819-70-5-1082_3
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Published: Ann Intern Med. 1969;70(5):1082-1083.
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