John Hampton, M.D.
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An increase in the adhesion of platelets to glass occurs in patients with arterial disease but also in a wide variety of other diseases.
Platelet electrophoretic mobility is increased by small concentrations of adenosine diphosphate (ADP) and noradrenaline and decreased by larger concentrations. The concentration of either agent that induces maximum platelet mobility can be used as an index of the sensitivity of the platelet to that agent, and on this basis three distinct patterns of abnormal platelet electrophoretic response have been identified in patients with conditions known to be associated with increased platelet adhesiveness.
1. In any acute illness
Hampton J. The Study of the Platelets of Patients with Arterial Disease.. Ann Intern Med. ;70:1083–1084. doi: 10.7326/0003-4819-70-5-1083_3
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Published: Ann Intern Med. 1969;70(5):1083-1084.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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