Gerhard Freund, M.D., F.A.C.P.
This content is PDF only. Please click on the PDF icon to access.
Progress in alcoholism research has been slow because of the lack of a suitable animal model of the alcohol withdrawal syndrome. This is the first description of an alcohol withdrawal syndrome induced in animals drinking alcohol. A liquid diet containing 40% calories as ethanol was the only source of calories and fluids for 20 adult female ICR mice for 3 months. The mice lost weight, from 27 to 30 g at the beginning of the experiment to 20 to 30 g at the time of withdrawal. During the 10 days before ethanol withdrawal all mice that developed a withdrawal reaction
Gerhard Freund. Alcohol Withdrawal Syndrome in Mice.. Ann Intern Med. 1969;70:1101. doi: 10.7326/0003-4819-70-5-1101_1
Download citation file:
Published: Ann Intern Med. 1969;70(5):1101.
Tobacco, Alcohol, and Other Substance Abuse.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use