WILLIAM WEISS, M.D., F.A.C.P.; DAVID A. COOPER, M.D., F.A.C.P.; KATHARINE R. BOUCOT, M.D., F.A.C.P.
Twelve teaching hospitals in Philadelphia reported histologically proved cases of bronchogenic carcinoma to the County Medical Society Subcommittee on Lung Cancer from 1956 to 1965. A study was made of the first 421 men who were operated on and had 5-year follow-up. Of these, 156 had thoracotomy only, and 265 had resections. Age, tissue type, and surgical procedure were examined in relation to operative risk and 5-year survival. Patients explored whose cancers were not resected were included because such patients have a significant operative mortality rate but no benefit. The overall operative mortality rate was 11%, and 5-year survival rate was 13%.
Operative risk increased with age but was essentially the same for the three tissue types and the type of surgery although it tended to be higher in patients with right pneumonectomy. Five-year survival was unrelated to age but was poor in men with undifferentiated carcinoma and better for those treated by lobectomy than for those who had pneumonectomy. Operative risk exceeded 5-year survival rate in men aged 70 and over, men with undifferentiated carcinoma, those explored but not resected, and in older men requiring right pneumonectomy. In these categories the therapeutic approach should be conservative.
WILLIAM WEISS, DAVID A. COOPER, KATHARINE R. BOUCOT. Operative Mortality and 5-Year Survival Rates in Men with Bronchogenic Carcinoma. Ann Intern Med. 1969;71:59–65. doi: 10.7326/0003-4819-71-1-59
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Published: Ann Intern Med. 1969;71(1):59-65.
Hematology/Oncology, Lung Cancer, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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